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A Guide To Tapering Off Methadone (With Dosing)

Stopping methadone should not be uncomfortable, but does take time — often many months. Patients that rush the process experience unpleasant methadone withdrawal symptoms and are at high risk for relapse.

Methadone Taper  |  Stop Methadone Cold Turkey  |  Preventing Relapse  |  Ask a Question

How to Discontinue Methadone Use

Pending a patient is set up to successfully manage their opioid addiction without methadone, the general protocol to prevent painful methadone withdrawal symptoms is to:

The dose should not be decreased more than once a week. If cravings or withdrawal symptoms are experienced, each step down can take several weeks. It’s never worth it to rush the process.

Example: Quickest Possible Methadone Taper for Patient On 60mg Dose 

WeekDose ReductionDose in mg

(While the timeline in this example can help avoid methadone withdrawal, it is faster than recommended for lasting sobriety).

How Long Does It Take To Fully Detox From Methadone?

How long it takes to taper off methadone depends on the dose and the comfort of the patient. For a base calculation, add one week for every 10mg the patient’s dose is above 40mg, then add 6-12 weeks.

Length of Methadone Tapers

Maintenance DoseQuickest Possible TaperFor Highest Success Rates
60mg9 weeks (2 months)6 months
120mg16 weeks (2.5 months)10 months

The research is clear that longer tapers have substantially higher rates of success, including tapers that take a full year and tapers that only drop doses every 3 weeks.

The goal is not “getting off methadone.” The goal is long-term recovery.

Why does it take so long to get off methadone?

Once a patient decides to stop methadone, they are usually very eager. The timeline can feel frustrating. However, a gradual methadone taper helps minimize any withdrawal symptoms and cravings. And, rushing the process almost always leads to relapse. 

It’s worth it to take a few extra weeks.

What Happens If You Stop Methadone Cold-Turkey?

Methadone is an opioid. Stopping any opioid cold turkey is likely to be painful and lead to relapse. The withdrawal symptoms for methadone are generally the same as other opioids, though may last longer. 

Methadone Withdrawal Symptoms

Days 1-2

Days 3-8

Days 9-15

Days 15+

Those quitting cold turkey are more likely to experience Post-Account Withdrawal Syndrome (opioid PAWS), where withdrawal symptoms like anxiety or fatigue can last two years or even be permanent.

Any intense methadone withdrawal symptoms can be avoided by tapering down from methadone over several months and with medical supervision.

Is Methadone Withdrawal Worse Than Opioid Withdrawal?

While withdrawal symptoms are similar for both methadone and other opioids, methadone withdrawal tends to be less intense with a less rapid onset. However, methadone stays in the body longer because it is a long-acting medication, so withdrawal symptoms may last longer.

How To Get Through Methadone Withdrawal

Any severe methadone withdrawal symptoms can be avoided altogether by going to a methadone clinic and tapering down slowly!

Despite what people might post on internet forums, there is no other helpful medication to end methadone withdrawal symptoms other than a methadone taper. Specific symptoms might be treatable without methadone but would still require a medical prescription — ie. Ondansetron (Zofran) for nausea.

The best advice is to find a methadone clinic to stop the struggle of methadone withdrawal before a relapse.

See also: What is a Methadone Clinic

How to Prevent Relapse After Stopping Methadone

A distressing withdrawal from methadone is likely to lead to relapse.  Patients tend to be successful when the taper is slow and they are surrounded by support

Extra support always ends better than a patient thinking they can handle it on their own. Here are some questions to consider before stopping methadone:

Methadone is always recommended to be tapered with a medication professional because:

Get Help With Your Methadone Taper

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Symetria doctors follow rigorous sourcing guidelines and cite only trustworthy sources of information, including peer-reviewed journals, court records, academic organizations, highly regarded nonprofit organizations, government reports and their own expertise with decades in the field.

Methadone maintenance treatment. (2023). Retrieved February 8, 2023, from website:

Nosyk, B., Sun, H., Evans, E., Marsh, D. C., Anglin, M. D., Hser, Y.-I., & Anis, A. H. (2012). Defining dosing pattern characteristics of successful tapers following methadone maintenance treatment: results from a population-based retrospective cohort study. Addiction, 107(9), 1621–1629.

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